Fabrication of three-dimensional microdisk resonators in calcium fluoride by femtosecond laser micromachining

We report on fabrication of on-chip calcium fluoride (CaF2) microdisk resonators using water-assisted femtosecond laser micromachining. Focused ion beam (FIB) milling is used to create ultra-smooth sidewalls. The quality (Q)-factors of the fabricated microresonators are measured to be 4.2x10^4 at wavelengths near 1550 nm. The Q factor is mainly limited by the scattering from the bottom surface of the disk whose roughness remains high due to the femtosecond laser micromachining process. This technique facilitates formation of on-chip microresonators on various kinds of bulk crystalline materials, which can benefit a wide range of applications such as nonlinear optics, quantum optics, and chip-level integration of photonic devices.Comment: 7 pages, 3 figure

Memperbaiki Saturasi Oksigen, Frekuensi Denyut Jantung, Dan Pernafasan Neonatus Yang Menggunakan Ventilasi Mekanik Dengan Terapi Musik

Improving Oxygen Saturation, Heart Rate, and Respiratory Rate of Neonates Using Mechanical Ventilation with Music Therapy. Neonates using mechanical ventilation cause of respiratory disorder experience oxygenation and heart rate problems. Interventions should be made in order to calm neonates so that the need of oxygen can be minimized, one of these interventions is music therapy. This study aimed to identify the effect of music therapy on oxygen saturation, heart rate and respiratory rate of neonates using mechanical ventilation. This quasi experiment study with a pretest-posttest design without control involved 13 neonates selected by consecutive sampling. Data collected through observation and analyzed by paired t test. There was a significant difference on the average of oxygen saturation, heart rate and respiratory rate of infants using mechanical ventilation before and after music therapy (p value <0,05). Music therapy can be used as a complementary medical therapies to improve oxygenation in neonates using mechanical ventilation

Weak Signal Detection Based on Adaptive Cascaded Bistable Stochastic Resonance System

AbstractStochastic resonance system is an effective method to extract weak signal, however, system output is directly influenced by system parameters. Aiming to this, a method about weak periodic signal extraction was developed based on adaptive stochastic resonance. Firstly cascaded stochastic resonance system was established in order to achieve better low-pass filtering effect. And then, variance of zero point distance was chosen as measurement index of cascade system. It's able to overcome the shortage that traditional adaptive stochastic resonance system needs to know the signal frequency beforehand. Also, it could obtain optimum system parameters adaptively. Basing on these parameters, input signal will be handled, and optimum output could be obtained. Furthermore, different periodic signal have been recognized, and finally the validity of the method is verified through simulation experiments

Expression of fatty acid synthesis genes and fatty acid accumulation in haematococcus pluvialis under different stressors

<p>Abstract</p> <p>Background</p> <p>Biofuel has been the focus of intensive global research over the past few years. The development of 4^thgeneration biofuel production (algae-to-biofuels) based on metabolic engineering of algae is still in its infancy, one of the main barriers is our lacking of understanding of microalgal growth, metabolism and biofuel production. Although fatty acid (FA) biosynthesis pathway genes have been all cloned and biosynthesis pathway was built up in some higher plants, the molecular mechanism for its regulation in microalgae is far away from elucidation.</p> <p>Results</p> <p>We cloned main key genes for FA biosynthesis in <it>Haematococcus pluvialis</it>, a green microalga as a potential biodiesel feedstock, and investigated the correlations between their expression alternation and FA composition and content detected by GC-MS under different stress treatments, such as nitrogen depletion, salinity, high or low temperature. Our results showed that high temperature, high salinity, and nitrogen depletion treatments played significant roles in promoting microalgal FA synthesis, while FA qualities were not changed much. Correlation analysis showed that acyl carrier protein (ACP), 3-ketoacyl-ACP-synthase (KAS), and acyl-ACP thioesterase (FATA) gene expression had significant correlations with monounsaturated FA (MUFA) synthesis and polyunsaturated FA (PUFA) synthesis.</p> <p>Conclusions</p> <p>We proposed that ACP, KAS, and FATA in <it>H. pluvialis </it>may play an important role in FA synthesis and may be rate limiting genes, which probably could be modified for the further study of metabolic engineering to improve microalgal biofuel quality and production.</p

NCP activates chloroplast transcription by controlling phytochrome-dependent dual nuclear and plastidial switches.

Phytochromes initiate chloroplast biogenesis by activating genes encoding the photosynthetic apparatus, including photosynthesis-associated plastid-encoded genes (PhAPGs). PhAPGs are transcribed by a bacterial-type RNA polymerase (PEP), but how phytochromes in the nucleus activate chloroplast gene expression remains enigmatic. We report here a forward genetic screen in Arabidopsis that identified NUCLEAR CONTROL OF PEP ACTIVITY (NCP) as a necessary component of phytochrome signaling for PhAPG activation. NCP is dual-targeted to plastids and the nucleus. While nuclear NCP mediates the degradation of two repressors of chloroplast biogenesis, PIF1 and PIF3, NCP in plastids promotes the assembly of the PEP complex for PhAPG transcription. NCP and its paralog RCB are non-catalytic thioredoxin-like proteins that diverged in seed plants to adopt nonredundant functions in phytochrome signaling. These results support a model in which phytochromes control PhAPG expression through light-dependent double nuclear and plastidial switches that are linked by evolutionarily conserved and dual-localized regulatory proteins

Skin-touch-actuated textile-based triboelectric nanogenerator with black phosphorous for durable biomechanical energy harvesting

Textiles that are capable of harvesting biomechanical energy via triboelectric effects are of interest for self-powered wearable electronics. Fabrication of conformable and durable textiles with high triboelectric outputs remains challenging. Here we propose a washable skin-touch-actuated textile-based triboelectric nanogenerator for harvesting mechanical energy from both voluntary and involuntary body motions. Black phosphorus encapsulated with hydrophobic cellulose oleoyl ester nanoparticles serves as a synergetic electron-trapping coating, rendering a textile nanogenerator with long-term reliability and high triboelectricity regardless of various extreme deformations, severe washing, and extended environmental exposure. Considerably high output (~250–880 V, ~0.48–1.1 µA cm−2) can be attained upon touching by hand with a small force (~5 N) and low frequency (~4 Hz), which can power light-emitting diodes and a digital watch. This conformable all-textile-nanogenerator is incorporable onto cloths/skin to capture the low output of 60 V from subtle involuntary friction with skin, well suited for users’ motion or daily operations

On-chip tuning of the resonant wavelength in a high-Q microresonator integrated with a microheater

We report on fabrication of a microtoroid resonator of high-quality (high-Q) factor integrated with an on-chip microheater. Both the microresonator and microheater are fabricated using femtosecond laser three-dimensional (3D) micromachining. The microheater, which is located about 200 micron away from the microresonator, has a footprint size of 200 micron by 400 micron. Tuning of the resonant wavelength in the microresonator has been achieved by varying the voltage applied on the microheater. The drifting of the resonant wavelength shows a linear dependence on the square of the voltage applied on the microheater. We found that the response time of the microresonator is less than 10 secs which is significantly shorter than the time required for reaching a thermal equilibrium on conventional heating instruments such as an external electric heater